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TikTok · Rowan Cheung· Rowan Cheung·· 3 天前AI 评分38

Red Queen Bio 用 AI 开发抗体药物,计划 2027 年启动人体试验

🦠 Red Queen Bio is using AI to develop antibody drugs that could help stop future pandemics, including threats that AI might help create. Starting with influenza, the company aims to target shared weaknesses across related viruses, potentially protecting against strains that haven’t emerged yet. Scientists test antibody candidates in the lab and feed results back into AI models to refine their designs. The goal is to build effective treatments that can be stockpiled before an outbreak begins. But the approach still needs testing in people, with human trials planned for 2027.

AI 导读

Red Queen Bio 正用 AI 开发抗体药物以应对未来大流行,先从流感(含禽流感)入手,瞄准相关病毒共有的分子弱点,或可覆盖尚未出现的毒株。实验室测试抗体候选物后把结果回馈 AI 模型迭代设计,目标是疫情暴发前完成药物储备。该方案仍需人体验证,人体试验计划于 2027 年开展。

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Rowan Cheung@rowancheung

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正文

以下是视频口播的自动转写,可能有错字。

So this startup is using ai to try to prevent the next pandemic, even one caused by a virus that ai helps create. It's called red queen bio, and it's developing antibody drugs starting with the bird flu and other influenzas.

Vaccines train your immune system to respond, but antibody drugs deliver defensive proteins directly, potentially providing immediate, temporary protection.

But how do you prepare for a virus that's never been seen? While related viruses can share molecular weak points, even when other parts change.

Those shared targets allow certain antibodies to recognize multiple strains, potentially including the ones that haven't emerged yet.

Basically, red queen scientists test antibody candidates in the lab, then feed the results back into ai models to improve the next designs.

The team also wants antibodies that bind more tightly to their targets, which could reduce the dose needed and help supplies go further.

Eventually, the goal is to stockpile these drugs before an outbreak starts. But that being said, the company still needs to demonstrate that its drugs are safe and effective for people.

It's really fascinating stuff, but designing a promising molecule is only useful if it becomes medicine before it's actually needed.

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来源:TikTok · Rowan Cheung · tiktok.com